3D Deconvolution

3D Deconvolution Hits 1216 views

DESCRIPTION


Name:      3D Deconvolution

Speciality: Upright microscope allowing 3D observation of fixed multi-labeled samples. 

Aknowlegment/Grant for this microscope: "We acknowledge the Nikon Imaging Center at Curie - CNRS, member of the national infrastructure France-BioImaging (https://ror.org/01y7vt929) supported by the French National Research Agency (ANR-24-INBS-0005 FBI BIOGEN).

Equipments:

Detectors Camera sCMOS : Prime BSi Express (Photometrics)

Sensor Gpixel GSENSE2020BSI Scientific CMOS sensor
Active Array Size 2048 x 2048 (4.2 Megapixel)
Pixel Area 6.5
μm x 6.5μm (42.25μm2)
Sensor Area 13.3mm x 13.3mm, 18.8mm diagonal
Peak QE% >95%
Read Noise
Correlated Multi-Sampling (CMS) 1.0 e- (Median)
1.1e- (RMS)
Combined/High Gain 1.6e- (Median)
1.8e- (RMS)
Full-Well Capacity
45,000e- (Combined Gain)
10,000e- (High Gain)
1,000e- (CMS)
Dynamic Range 25,000:1 (Combined Gain)
Bit Depth
16-bit (Combined Gain)
12-bit (CMS)
11-bit (High Gain)
Readout Mode Rolling Shutter, Effective Global Shutter,
Programmable Scan Mode
Binning 2x2 (on FPGA
Microscope NI-E Upright microscope with maximum FOV of 18 mm
Options Motorized stage XYZ
Software NIS Elements AR, 2D & 3D decovolution, NIS.ai,  Clarify.ai, Denoise.ai, JOBS, GA3, Large images
Objective 10x Plan Fluor , NA : 0.30 , WD : 16.0 , Dry , Phase
20x Plan Apo VC  , NA : 0.75 , WD : 1.0 , Dry , DIC
40x Plan Fluor , NA : 1.30 , WD : 0.24 Oil , DIC
60x Plan Apo VC , NA : 1.40 , WD : 0.13 , oil , DIC
100x Plan Apo VC , NA : 1.40 , WD : 0.13 , oil , DIC
Filter DAPI   377/50   409   470/40
GFP   472/30   495   520/35
Cy3   535/40   565   590/40
mcherry   562/40   593   641/75
CY5   628/40   660   692/40

Data transfert:

Connect to the isiserver.net :Login by entering : curie.net\your Curie's login and Password

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Booking rules:

Slots can be booked 2 weeks in advance for all teams.
Slots will not be charged if cancelled more than 24 hours in advance.
Slots will be charged if cancelled less than 24 hours in advance.

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How to connect to the shared file on the microscope's computer (only in the Burg building):
On your own PC:
- You have to right click on "PC" and "Map a network drive" : 
Enter the network address of the microscope to access to the users folder:  \\3Ddec-NIC\users2 
- Select both options : "Reconnect at logon" and "Connect using different credentials"

- Type the username "invite" and the usual password of the facility. 

COMMENTS

No preferential booking
No booking restriction

PROVIDER
AFFILIATED ORGANIZATIONS
Institut Curie